Patent · US Expired

Nonionic 5-C-substituted 2,4,6-triiodoisophthalic acid derivatives

US5047228A · kind A · utility

12Cited by

5References

15Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Heinz Gries · Berlin, DE
Heinrich Pfeiffer · Eppingen, DE
Ulrich Speck · Berlin, DE
Wolfgang Mutzel · Berlin, DE

Key dates

Filing date	Mar 2, 1989
Grant date	Sep 10, 1991
Priority date	—
Expiry date	Mar 2, 2009

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C233/69
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Nonionic compounds of the formula ##STR1## wherein X is --CONR.sub.1 R.sub.2, --COOR.sub.3, --CH.sub.2 NHR.sub.7 or --CH.sub.2 OH; Y is --1R.sub.1 R.sub.2 or --OR.sub.3 ; and Z is --NR.sub.1 R.sub.2, --NHR.sub.7 or --OR.sub.3 ; and wherein R.sub.1 R.sub.2 and R.sub.3 in X, Y or Z, and R.sub.7 in X and Z, are identical or different, R.sub.1 and R.sub.2, and each is hydrogen, C.sub.1-6 -alkyl or C.sub.2-8 - alkyl substituted by 1-5 OH groups and/or by a C.sub.1-3 -alkoxy group; R.sub.3 is C.sub.1-4 -alkyl or C.sub.2-4 -alkyl substituted by 1-2 OH groups and/or by a C.sub.1-3 -alkoxy group; and R.sub.7 is an acyl group of a C.sub.2-5 OH group and/or by a C.sub.1-3 -alkoxy group are highly advantageous X-ray contrast agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.