Monoclonal antibodies with specificity affinity for human carcinoembryonic antigen
US5047507A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 4, 1989 |
| Grant date | Sep 10, 1991 |
| Priority date | — |
| Expiry date | Jan 4, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns novel monoclonal antibodies with high specificity to and affinity for human carcinoembryonic antigen (CEA), derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines secreting the antibodies, and processes for the preparation of said cell lines. The monoclonal antibodies of the invention and their derivatives are useful in the diagnosis and therapy of cancer and serial monitoring of cancer patients for recurrent disease or response to therapy. Test kits and pharmaceutical compositions containing said monoclonal anti-CEA antibodies are also subject of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.