Potentiation of the thrombolytic effect of prourokinase type plasminogen activators by streptokinase
US5051264A · kind A · utility
5Cited by
1References
10Claims
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Key dates
| Filing date | Nov 2, 1988 |
| Grant date | Sep 24, 1991 |
| Priority date | — |
| Expiry date | Nov 2, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21073
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The thrombolytic effect of known plasminogen activators such as tissue plasminogen activator (t-PA), prourokinase and modifications of t-PA and prourokinase is enhanced dramatically and unexpectedly when combined with streptokinase. The body is treated with a combination streptokinase and one or more plasminogen activators of the t-PA or prourokinase type to achieve an enhanced effect which has advantage in thrombolytic therapy including the treatment of myocardial infarction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.