Patent · US Expired

Inulin compositions in gamma polymorphic form

US5051408A · kind A · utility

23Cited by
0References
16Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 30, 1990
Grant dateSep 24, 1991
Priority date
Expiry dateMar 30, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08B37/0054
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A process for preparing gamma inulin comprising the steps of (a) recrystallizing crude inulin from water at a temperature below 37.degree. C. to obtain a suspension, (b) heating the suspension at a temperature of from about 25.degree. to 45.degree. C. for about 1-3 days, (c) further heating the suspension at a temperature of about 40.degree. to 55.degree. C. for about 0.5 to 1.5 hours, and (d) isolating insoluble gamma inulin from the suspension. A composition comprising particles of inulin or an inulin derivative in the gamma polymorphic form is characterized in that the particles have a low rate of solution in aqueous media above 30.degree. C., particularly above 37.degree. C. The composition is effective as the active component of an immunotherapeutic preparation for activation of the alternative pathway of complement, or for antitumor treatment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.