Inhibition of restenosis by ultraviolet radiation
US5053033A · kind A · utility
399Cited by
14References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 10, 1990 |
| Grant date | Oct 1, 1991 |
| Priority date | — |
| Expiry date | Oct 10, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/0661
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Restenosis following angioplasty can be inhibited by reducing the proliferation of smooth muscle cells in the blood vessel walls at an angioplasty site, and such reduction in cell proliferation can be accomplished by irradiating the angioplasty site with radiation in the ultraviolet (UV) wavelength range. The ultraviolet radiation is preferably delivered via an optical fiber or other waveguide incorporated, for example, into a percutaneous catheter. In operation, the ultraviolet radiation kills smooth muscle cells at the site, thereby reducing the risk of restenosis, while minimizing damage to surrounding tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.