Fused heterotricyclic imides with psychotropic activity and intermedrates thereof
US5053508A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 9, 1990 |
| Grant date | Oct 1, 1991 |
| Priority date | — |
| Expiry date | Mar 9, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/93
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are disclosed compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 taken together represent ##STR2## R.sup.3 and R.sup.4 are hydrogen; R.sup.5 is 2-pyridinyl, 2-pyrazinyl, 2-pyrimidinyl, 3-pyridazinyl or any of the foregoing R.sup.5 moieties substituted by lower alkyl, lower alkoxy, halo lower alkyl, cyano, nitro or halo; PA1 X, Y and Z are, independently, N, S, O, NR.sup.6, SO, SO.sub.2, CR.sup.6 or CH.sub.2 ; PA1 A is lower alkylene, O or S; PA1 R.sup.6 is hydrogen, lower alkyl, aryl, aralkyl; PA1 m is 3-7; and the pharmaceutically acceptable salts thereof, and their use as antipsychotic/-anxiolytic agents having a low liability for extrapyramidal side effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.