Patent · US Expired

Benzo[1,8]naphthyridine derivatives, their preparation and compositions containing them

US5053509A · kind A · utility

4Cited by
1References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 30, 1990
Grant dateOct 1, 1991
Priority date
Expiry dateOct 30, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

New benzo[b][1,8]naphthyridine derivatives of general formula (I), in which R.sub.1 is a hydrogen atom or a hydroxyl or alkyl radical, R.sub.2 is a hydrogen atom or an alkyl, fluoroalkyl, cycloalkyl (3 to 6 C), alkyloxy or alkylamino radical, R.sub.3 is a phenyl or phenylalkyl radical substituted with one or more halogen atoms or alkyl, cycloalkyl (3 to 6 C), alkyloxy, cyano, amino, alkylamino, dialkylamino, alkyloxyalkyl, hydroxyalkyl, hydroxyalkyloxy, methylenedioxy, aminoalkyl, alkylaminoalkyl or dialkylaminoalkyl radicals, or R.sub.3 is a heterocyclic radical, and R.sub.4 is a hydrogen atom or a fluorine atom, the alkyl radicals (1 to 4 C) being linear or branched, their salts, their preparation and compositions containing them. These new products are useful as antimicrobials, or in the treatment of AIDS. ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.