Avermectin derivatives
US5057499A · kind A · utility
10Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 1989 |
| Grant date | Oct 15, 1991 |
| Priority date | — |
| Expiry date | Jun 2, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are disclosed novel avermectin derivatives wherein the outer oleandrose ring of avermectin or avermectin monosaccharide is homologated by addition of diazomethane to 4"- or 4'-oxo-avermectin to afford the perhydrooxepine derivatives. The homologated avermectins can then be further derivatized to afford additional novel avermectins. The new compounds are potent antiparasitic agents, in particular, the compounds are anthelmintic, insecticidal and acaricidal agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.