Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5057509A · kind A · utility
20Cited by
1References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1990 |
| Grant date | Oct 15, 1991 |
| Priority date | — |
| Expiry date | Apr 9, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carbonanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.