Macrolide compounds
US5057536A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 9, 1989 |
| Grant date | Oct 15, 1991 |
| Priority date | — |
| Expiry date | May 9, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (1) ##STR1## and salts thereof, wherein R.sup.1 represents a methyl, ethyl or isopropyl group; PA1 Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## where R.sup.2 represents a hydrogen atom or a group OR.sup.8 (where OR.sup.8 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >C.dbd.O, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.9 (where R.sup.9 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.9 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--; PA1 R.sup.4 represents a group OR.sup.8 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent >C.dbd.O or >C.dbd.NOR.sup.9a (where R.sup.9a is as defined above for R.sup.9); PA1 R.sup.6 represents a hydrogen atom and R represents --CH.sub.2 OH, --CHO, --CO.sub.2 H or a carboxylic acid ester or amide group; or R.sup.6 represents a hydroxyl …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.