Expression of human proapolipoprotein A-I
US5059528A · kind A · utility
31Cited by
0References
15Claims
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Assignee
Inventors
Key dates
| Filing date | May 26, 1988 |
| Grant date | Oct 22, 1991 |
| Priority date | — |
| Expiry date | May 26, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides recombinant DNA sequences comprising a sequence which codes for human proapolipoprotein A-I wherein part of the natural coding sequence has been replaced by a DNA fragment coding for the same amino acids but consisting of a different nucleotide sequence such as to reduce or prevent formation of hairpins, cloning and expression vectors containing these DNA sequences, cell cultures or microorganisms transformed with these expression vectors and processes using the same for the production of proapolipoprotein A-I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.