7-(4-oxa or 4-thia-2,7-diazabicyclo[3.3.0]oct-2-en-3-yl)-3-quinolone-and-naphthyrido ne-carboxylic acid derivatives as antibacterial agents and feed additives

US5059597A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Uwe Petersen · Leverkusen, DE
• Thomas Schenke · Odenthal, DE
• Andreas Krebs · Odenthal, DE
• Klaus Grohe · Odenthal, DE
• Michael Schriewer · Odenthal, DE
• Ingo Haller · Wuppertal, DE
• Karl G. Metzger · Wuppertal, DE
• Rainer Endermann · Wuppertal, DE
• Hans-Joachim Zeiler · Velbert, DE

Key dates

• Filing date: Sep 10, 1990
• Grant date: Oct 22, 1991
• Expiry date: Sep 10, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives, of the formula ##STR1## in which X.sup.1 is halogen, PA0 X.sup.2 is hydrogen, halogen, amino or other radical, PA0 R.sup.1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical, PA0 R.sup.2 is hydrogen, alkyl or a dioxolylmethyl radical, PA0 R.sup.3 is ##STR2## and A is N, CH, C-halogen, or the like, or forms a bridge with R.sup.1, and addition products thereof.