Affinity matrices of modified polysaccharide supports
US5059654A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 16, 1989 |
| Grant date | Oct 22, 1991 |
| Priority date | — |
| Expiry date | Feb 16, 2009 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/386
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention is directed to a modified polysaccharide material which comprises: (1) polysaccharide covalently bonded to a synthetic polymer; (2) the synthetic polymer being made from (a) a polymerizable compound which is capable of being covalently coupled directly or indirectly to said polysaccharide, and (b) one or more polymerizable compounds containing (i) a chemical group capable of causing the covalent coupling of the compound (b) to an affinity ligand or a biologically active molecule or (ii) a hydrophobic compound. The invention is also directed to devices for the chromatographic separation of at least two components of a mixture comprising the modified polysaccharide material of the invention, wherein the device is configured for radial or tangential flow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.