Method of isolating CA 125 antigen
US5059680A · kind A · utility
13Cited by
1References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 24, 1986 |
| Grant date | Oct 22, 1991 |
| Priority date | — |
| Expiry date | Nov 24, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/853
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A preparation of an isolated immunoreactive CA 125 Antigen, and a method of isolating it is disclosed. CA 125 Antigen is a glycoprotein having a molecular weight of about 200kD, and a carbohydrate-content of about 24%. The CA 125 Antigen is isolated from a cell culture medium by acid precipitation, and is subsequently purified by size exclusion chromatography and immunoaffinity chromatography.
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