Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5061701A · kind A · utility
46Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1990 |
| Grant date | Oct 29, 1991 |
| Priority date | — |
| Expiry date | Apr 9, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J51/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6-hydroxy-7-keto-derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.