Covalent attachment of anticoagulants and the like onto biomaterials
US5061750A · kind A · utility
30Cited by
4References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1990 |
| Grant date | Oct 29, 1991 |
| Priority date | — |
| Expiry date | Jul 18, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L33/0047
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A substrate for medical devices and a process for making the substrate is provided, the substrate having on at least part of its surface a blood-compatible surface produced by coupling a physiologically active substance to the surface. The physiologically active substance is one having an inhibitory effect on the formation of blood clots and/or is capable of breaking down blood clots formed. The physiologically active substance is bonded to a polyacid, and the polyacid is attached to the surface by a covalent bond.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.