Renin inhibitors, method for using them, and compositions containing them
US5063207A · kind A · utility
35Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 1989 |
| Grant date | Nov 5, 1991 |
| Priority date | — |
| Expiry date | Jul 24, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0227
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention concerns novel renin-inhibitory peptides which are useful for treating renin-associated hypertension, congestive heart failure, hyperaldosteronism and diseases caused by retroviruses including HTLV-I and -III. Processes for preparing the peptides, novel intermediates useful in the preparation thereof, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, congestive heart failure, or hyperaldosteronism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.