Process for preparation of novel angiotensin II antagonists
US5066586A · kind A · utility
5Cited by
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4Claims
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Key dates
| Filing date | Aug 20, 1990 |
| Grant date | Nov 19, 1991 |
| Priority date | — |
| Expiry date | Aug 20, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/182
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel biotransformation compounds I, II, III and IV are prepared by fermenting 3-[(2'-tetrazol-5-yl-biphenyl-4-yl) methyl]-7-methyl-2-propyl-3H-imidzao [4,5-b]pyridine in a culture of Streptomyces sp., Accession Number ATCC 55041. ##STR1## These novel compounds are Angiotensin II antagonists useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.