Patent · US Expired

Gas driven microprojectile accelerator and method of use

US5066587A · kind A · utility

20Cited by
3References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 26, 1990
Grant dateNov 19, 1991
Priority date
Expiry dateJan 26, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/8207
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A foreign substance, such as DNA, is injected into plant cells or tissue by a biological ballistical insertion technique. High pressure propellant gas is employed to accelerate the macroprojectile containing microprojectiles coated with the foreign substance. A movable macroprojectile stop mechanism is provided between an upper injection chamber and a lower sample-holding chamber so that multiple shots of macroprojectiles can be made without disrupting the vacuum in the lower chamber. The stop mechanism includes removable stopper plugs for stopping the macroprojectile. A vacuum seal is provided between the stop mechanism and the lower chamber.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.