Stabilization of enteric coated dosage form
US5068110A · kind A · utility
116Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 14, 1989 |
| Grant date | Nov 26, 1991 |
| Priority date | — |
| Expiry date | Jul 14, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/4891
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a stabilized enteric-coated pharmaceutical dosage form and processes for the preparation thereof. Dissolution stability after storage of the dosage form under high stress conditions is improved by an enteric-coated dosage form having an enteric coating wherein the coating is of the acrylic resin kind of from 14 mg/cm.sup.2 to 24 mg/cm.sup.2 or an enteric coating wherein the coating is of the acetate kind of from 14 mg/cm.sup.2 to 24 mg/cm.sup.2 and having a second coating of hydrophilic coating for example, hydroxypropyl cellulose, hydroxymethyl cellulose or hydroxypropylmethyl cellulose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.