"Recombinant DNA vectors encoding a 4""-O-isovaleryl acylase derived from a carbomycin biosynthetic gene, designated carE, for use in streptomyces and other organisms"
US5068189A · kind A · utility
3Cited by
1References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 13, 1988 |
| Grant date | Nov 26, 1991 |
| Priority date | — |
| Expiry date | May 13, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The carE gene of Streptomyces thermotolerans has been isolated and used to construct recombinant DNA expression vectors. The carE gene encodes 4"-O-isovaleryl acylase activity important in the biosynthesis of a number of useful antibiotics. The carE gene can be used not only to construct recombinant cells with an increased ability to produce the acylase enzyme but also to construct recombinant cells with the ability to produce novel antibiotic compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.