Patent · US Expired

Dot matrix membrane cell expansion and maintenance vessel

US5068195A · kind A · utility

29Cited by
19References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 2, 1988
Grant dateNov 26, 1991
Priority date
Expiry dateNov 2, 2008

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12M29/04
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

There is disclosed a perfusable cell culture device capable of expansion and maintenance of biological cells, including mammalian, microbial, plant and insect cells in culture. The device comprises an upper and lower polymeric film layer and a gas and liquid permeable flow divider membrane. The flow divider membrane is affixed between the upper and lower polymeric layers and to the lower polymeric layer in a manner providing channels for fluid distribution of culture medium which is perfused at a controlled rate, uniformly across the flow divider membrane and to a bed of cells dispersed on the flow divider membrane.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.