Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
US5068232A · kind A · utility
4Cited by
3References
8Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 10, 1990 |
| Grant date | Nov 26, 1991 |
| Priority date | — |
| Expiry date | Apr 10, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D205/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new 2-substituted alkyl-3-carboxy carbapenems having the formula: ##STR1## with R.sup.1, R.sup.2, R.sup.3, X and Y defined hereafter as antibiotics and beta lactamase inhibitors produced by a novel Michael addition-elimination reaction of a substituted allyl azetidinone in the reaction shown: ##STR2## with R.sup.1, R.sup.2, Q, X and Y defined hereafter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.