Separation of an organic acid from a fermentation broth with an anionic polymeric adsorbent
US5068419A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 8, 1989 |
| Grant date | Nov 26, 1991 |
| Priority date | — |
| Expiry date | May 8, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/47
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An organic acid is separated from a fermentation broth by using an adsorbent comprising a water-insoluble macroreticular or gel weakly basic anionic exchange resin possessing tertiary amine or pyridine functional groups or a strongly basic anionic exchange resin possessing quaternary amine functional groups. The resins are in sulfate form and have a cross-linked acrylic or styrene resin matrix. The organic acid is desorbed with water or dilute inorganic acid, e.g., sulfuric. The pH of the feed is maintained below the first ionization constant (pKa.sub.1) of the organic acid to obtain high selectivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.