Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3- and -4-amine as gastric prokinetic, antiemetic, and anxiolytic agents
US5070095A · kind A · utility
9Cited by
2References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 12, 1990 |
| Grant date | Dec 3, 1991 |
| Priority date | — |
| Expiry date | Dec 12, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D453/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 1-(azabicyclo[2.2.2]oct-3- or -4-yl)benzamides substituted on the benzene ring with the basic substituted aminomethyleneamino group have been found to be useful in treating emesis, including emesis due to chemical and radiation anticancer therapy, anxiety, and impaired gastric emptying. These compounds are represented by Formula I below. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.