Cryoprotective agent and its use in cryopreservation of cellular matter
US5071741A · kind A · utility
76Cited by
10References
28Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 18, 1988 |
| Grant date | Dec 10, 1991 |
| Priority date | — |
| Expiry date | Apr 18, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/108331
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
A novel class of nonpermeating cryoprotectants which, when mixed with certain known penetrating cryoprotectants, provide a useful medium for protection of living cells during a cryopreservation process. Algae-derived polysaccharides such as agarose and alginate are useful as nonpermeating cryoprotectants as they form a gel matrix when cooled, protect against ice crystal formation, and yield improved viability of cells when thawed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.