Mixed baculovirus compositions and uses thereof
US5071748A · kind A · utility
21Cited by
0References
17Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 15, 1989 |
| Grant date | Dec 10, 1991 |
| Priority date | — |
| Expiry date | May 15, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/14143
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A mixed composition polyhedral inclusion body (PIB) is provided which contains a mixture of nucleocapsids of at least two genetically distinct baculoviruses. At least one of the baculoviruses is genetically engineered to contain at least one heterologous gene. Followed ingestion of the mixed composition PIB by an insect host, a mixed viral infection ensues in the insect permitting the production therein of additional copies of the mixed composition PIB and the production of a heterologous protein encoded by the heterologous gene present in at least one of the baculoviruses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.