Process for the production of L-amino acids

US5071752A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Uwe Klages · Berlin, DE
• Alfred Weber · Wien, AT
• Ludwig Wilschowitz · Alzenau, DE

Key dates

• Filing date: Sep 23, 1988
• Grant date: Dec 10, 1991
• Expiry date: Sep 23, 2008

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/872
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Process is described for the production of L-amino acids of general formula I ##STR1## in which R.sub.1 means an alkyl radical with at most 12 carbon atoms optionally substituted by hydroxy groups, mercapto groups, halogen atoms, amino groups, carbonyl groups or guanidino groups and/or interrupted by oxygen atoms, nitrogen atoms or sulfur atoms, and in the case of mercapto compounds of formula I also their dithio compounds, characterized in that the microorganism Nocardia spec. DSM 3306 or its enzymes are allowed to act on a D,L-imidazolidinedione derivative of general formula II ##STR2## in which R.sub.1 has the above-named meaning or, in the case of mercapto compounds of formula II, also in their dithio compounds.