2,3-dihydro-3-arylalkylaminoalkyl-4H-1,3-benzoxazin-4-one derivatives, their preparation and their application as medicinal products which are useful in therapy
US5071850A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 6, 1989 |
| Grant date | Dec 10, 1991 |
| Priority date | — |
| Expiry date | Sep 6, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D265/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the new 3-arylalkylaminoalkyl-4H-1,3-benzoxazin-4-one derivatives of general formula ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be identical or different, denote a hydrogen, a branched or unbranched lower alkyl group or an alkyloxy, halo, nitro, amino, acylamino or dialkylamino group, and R.sub.1 and R.sub.2 on one hand and R.sub.3, R.sub.4 on the other hand can fuse to give a divalent group and more especially --OCH.sub.2 O--, --OCH.sub.2 CH.sub.2 O-- and --CH.dbd.CH--CH.dbd.CH--; R.sub.5 and R.sub.6, which may be identical or different, denote a hydrogen, a saturated or unsaturated, branched or unbranched alkyl group containing from 1 to 15 carbon atoms or a cycloalkyl group, and R.sub.5 and R.sub.6 can fuse to give a --(CH.sub.2).sub.p -- group with p=2 to 7; R.sub.7 denotes a hydrogen, a saturated or unsaturated, branched or unbranched alkyl group containing from 1 to 15 carbon atoms, a cycloalkyl group, a substituted or unsubstituted aryl and a substituted or unsubstituted arylalkyl; the values of m and n, which may be identical or different, can vary from 1 to 4 inclusive; as well as the therapeutically acceptable organic or i…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.