Octopeptide exhibiting antimypertensive activity
US5071955A · kind A · utility
2Cited by
0References
5Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 9, 1989 |
| Grant date | Dec 10, 1991 |
| Priority date | — |
| Expiry date | Jun 9, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel peptide possessing excellent antihypertensive activity is disclosed. The peptide has the formula: EQU Pro-Thr-His-Ile-Lys-Trp-Gly-Asp (I) and can be prepared by purifying a fluid extracted from fish tissues or by combining constituting amino acids by a peptide synthesis method. It exhibits excellent ACE inhibitory activity, low toxicity, and good stability, and is thus an extremely useful and effective antihypertensive substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.