Preparation of intermediates and the synthesis of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidines
US5071990A · kind A · utility
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5Claims
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Key dates
| Filing date | Oct 4, 1990 |
| Grant date | Dec 10, 1991 |
| Priority date | — |
| Expiry date | Oct 4, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidines of the formula ##STR1## which comprises reacting a compound of the formula ##STR2## with glyoxal of the formula ##STR3## in a solvent to give the addition product ##STR4## and reducing such addition product (II) with a hydrogen donor reducing agent to produce the intermediates of the formula and then the end product (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.