Method of preparing oral dosage forms with a granulating composition
US5073377A · kind A · utility
38Cited by
3References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 4, 1990 |
| Grant date | Dec 17, 1991 |
| Priority date | — |
| Expiry date | Oct 4, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2009
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rapid disintegration or dispersion are important factors. It is useful for tablets containing ingredients which are difficult to compress and is particularly useful for formulating swallowable tablets of a single non-soluble ingredient such as calcium carbonate. Disintegration times are markedly decreased.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.