Continuous preparation of solid pharmaceutical forms

US5073379A · kind A · utility

Assignee

• BASF SE

Inventors

• Roger Klimesch · Ransbach-Baumbach, DE
• Gerhard Bleckmann · Lampertheim, DE
• Karl-Peter Farwerck · Worms, DE
• Lothar Schlemmer · Frankenthal (Pfalz), DE
• Axel Sanner · Bischofswerda, DE

Key dates

• Filing date: Aug 25, 1989
• Grant date: Dec 17, 1991
• Expiry date: Aug 25, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61J2200/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A mixture of one or more pharmaceutical active compounds and one or more thermoplastic polymers is tabletted by a process in which the mixture is extruded and the still moldable extrudate is pressed to give tablets, between two belts, or a belt and a roller, which make contact in parts, rotate in opposite directions and run parallel along the contact zone, the shape-imparting indentations, which may be present in complementary pairs, being located in both or in only one of the revolving shape-imparting elements.