Method and equipment for producing bioactive suspensions

US5074474A · kind A · utility

Assignee

• VEB Berlin-Kosmetik · DE

Inventors

• Karin Golz · Monaco, MC
• Rainer Jung · Berlin, DE
• Sebastian Kaehler · Berlin, DE
• Frank Raddatz · Berlin, DE
• Wilhelm Schelle · Berlin, DE
• Frank Vogel · Boulder, US
• Renate Winkler · Berlin, DE

Key dates

• Filing date: Aug 12, 1988
• Grant date: Dec 24, 1991
• Expiry date: Aug 12, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N1/06
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Biological material is suspended in a liquid and, in the presence of reverberative bodies suspended in the suspension of biological material, subjected to ultrasound thereby to disintegrate the biological material. The disintegration is conducted in a spherical chamber at approximately the center of which is the radiating surface of a sonotrode. The diameter of the chamber is at least three times the diameter of the radiating surface and the radiating surface faces the bottom of the chamber. The suspension of the biological material is pumped upwards through the chamber.