Patent · US Expired

Bolus for releasing a biologically active substance into a liquid environment

US5074857A · kind A · utility

7Cited by
8References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 3, 1986
Grant dateDec 24, 1991
Priority date
Expiry dateJun 3, 2006

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M31/002
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A bolus for releasing a biologically active substance into a liquid environment according to this invention comprising an elongate core, at least one end of which is frustoconical and a liquid impervious casing at one end and open at the other disposed about the core, the bolus being so constructed that, in use, the casing is progressively shed as the core retreats, thereby releasing the active substance at a rate which varies over at least one time period, the casing being so structured as to retain its integrity without disintegrating in the absence of any support provided by the core.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.