Somnogenic fragment of interleukin-1.beta.
US5075288A · kind A · utility
6Cited by
11References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 5, 1990 |
| Grant date | Dec 24, 1991 |
| Priority date | — |
| Expiry date | Sep 5, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A protein fragment for inducing sleep in mammals comprising a fragment of interleukin-1 .beta. from about amino acid 208 to about amino acid 240 and its physiologically active derivatives. The fragment comprises the amino acids sequence: ##STR1## The protein fragment may be derived by synthetic methods and a cysteine residue may be attached to the last threonine residue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.