Method for treating urinary obstruction
US5075308A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 15, 1990 |
| Grant date | Dec 24, 1991 |
| Priority date | — |
| Expiry date | Feb 15, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for treating urinary obstruction by administering a 2-(4-phenyl-1-piperazinylalkyl)aminopyrimidine derivative represented by the formula ##STR1## wherein R.sub.1 and R.sub.3 may be the same or different and independently represent hydrogen, halogen, an amino group, a hydroxyl group, a straight or branched chain lower alkyl group, a straight or branched chain lower alkoxy group, or a straight or branched chain hydroxy-lower alkyl group, R.sub.2 represents hydrogen, halogen, a carboxyl group, a straight or branched chain lower alkyl group, a straight or branched chain lower alkylcarbonyl group, or a straight or branched chain lower alkyloxycarbonyl group, R.sub.4 and R.sub.5 may be the same or different and independently represent hydrogen, halogen, a straight or branched chain lower alkyl group, or a straight or branched chain lower alkoxy group, and n represents an integer of 2 to 6 or a pharmaceutically acceptable acid addition salt thereof to a mammal including a human afflicted with urinary obstruction. The aminopyrimidine derivatives have a selective activity on the .alpha..sub.1 -adrenoceptors in the urinary tracts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.