Pyridinyl-quinolone compounds, their preparation and use
US5075319A · kind A · utility
8Cited by
8References
13Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 13, 1989 |
| Grant date | Dec 24, 1991 |
| Priority date | — |
| Expiry date | Sep 13, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C49/807
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Fluorinated 1-cyclopropyl-7-(substituted-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinecarbo xylic acids of the formula ##STR1## wherein R is hydrogen, R' and R" are hydrogen or fluoro, or other groups and Z is 3- or 4-pyridinyl substituted by alkyl groups or substituted alkyl groups, are superior antibacterial agents. They are prepared via a coupling reaction between the corresponding esters (R=alkyl) having a halo group in the 7-position and a substituted (trialkylstannyl)pyridine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.