Process for the preparation of N-acylphosphinothricin diesters

US5075485A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Manfred Bohshar · Kelkheim, DE
• Heinz Erpenbach · Cologne, DE
• Erhard Jagers · Bornheim, DE
• Hanss-Jerg Kleiner · Kronberg, DE
• Hans-Peter Koll · Hürth, DE

Key dates

• Filing date: Jun 29, 1989
• Grant date: Dec 24, 1991
• Expiry date: Jun 29, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/3211
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In order to prepare N-acylphosphinothricin diesters, acetals of methyl-(3-oxopropyl)phosphinic acid esters of the formula ##STR1## are reacted in a dipolar aprotic solvent with a carboxylic acid amide and carbon monoxide in the presence of hydrogen gas using a cobalt compound as a catalyst, where the radical R' is alkyl or aryl or aralkyl.