Nonionic X-ray contrast agents, compositions and methods
US5075502A · kind A · utility
14Cited by
5References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 13, 1989 |
| Grant date | Dec 24, 1991 |
| Priority date | — |
| Expiry date | Dec 13, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/273
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Triiodinated isophthalamide derivatives, useful as X-ray contrast agents, having at least one amide group derived from the amino-alcohol, 3-(N-2-hydroxyethyl)amino-1,2-propanediol, which provides high water solubility and low mammalian toxicity, and methods of preparing them. Methods of preparing 3-(N-2-hydroxyethyl)amino-1,2-propanediol are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.