Process for the preparation of O-substituted hydroxylamines
US5075504A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 18, 1990 |
| Grant date | Dec 24, 1991 |
| Priority date | — |
| Expiry date | Jun 18, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C259/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
O-substituted hydroxylamines of the formula I EQU H.sub.2 NOR.sub.1 (I) in which PA0 R.sub.1 is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 haloalkyl, --CH.sub.2 CR.sub.2 .dbd.CR.sub.3 R.sub.4 or --CH.sub.2 C.tbd.CR.sub.5 ; PA0 R.sub.2 is hydrogen, halogen or methyl; PA0 R.sub.3 is hydrogen, halogen or methyl;l PA0 R.sub.4 is hydrogen, halogen or methyl; and PA0 R.sub.5 is hydrogen, methyl or ethyl, EQU R.sub.6 --CN (II) in which R.sub.6 is C.sub.1 -C.sub.4 alkyl, phenyl or benzyl, is reacted with an alcohol of the formula III EQU R.sub.7 --OH (III) in which R.sub.7 is C.sub.1 -C.sub.5 alkyl, benzyl or C.sub.1 -C.sub.4 alkoxyethyl, in an organic solvent which is only sparingly miscible with water or not at all, in the presence of hydrogen halide HX, the suspension obtained of the iminoester hydrohalide of the formula IV ##STR1## in which R.sub.6 and R.sub.7 are as defined above and X is chlorine, bromine or iodine, is added at a controlled rate to an aqueous suspension of a carbonate or hydrogen carbonate at a temperature of from -3.degree. to +5.degree. C., an aqueous solution of a hydroxylamine salt is added to the mixture obtained at a temperature of from -20.degree. to -5.degree. …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.