Biocompatible composite material and a method for producing the same
US5077132A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 7, 1989 |
| Grant date | Dec 31, 1991 |
| Priority date | — |
| Expiry date | Nov 7, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC03C2214/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biocompatible composite material comprising a substrate having a glass-hydroxyapatite ceramic layer disposed thereon, and optionally having an intermediate glass layer between the substrate and the layer. The glass-hydroxyapatite ceramic layer comprises a continuous glass phase having a hydroxyapatite ceramic dispersed therein, said hydroxyapatite ceramic having a calcium/phosphorous molar ratio of 1.50 to 1.75, wherein said hydroxyapatite ceramic is comprised mainly of hydroxyapatite. The surface portion of the layer is in a roughened state having voids and having the hydroxyapatite ceramic exposed. The composite material may be produced by a method comprising applying a blend of a powdery glass with a hydroxyapatite ceramic to the surface of a substrate with or without a glass layer disposed thereon, firing the resulting coated substrate and subjecting the fired coated substrate to an etching action with an acid. The composite material is useful as a bone substitute material for the reconsutrction of bone defects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.