Beta-lactam derivatives of the 4-acylcephem sulphone and 3-acylpenam sulphone-type
US5077286A · kind A · utility
17Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1989 |
| Grant date | Dec 31, 1991 |
| Priority date | — |
| Expiry date | Apr 10, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formulae Ia and Ib ##STR1## wherein A is hydrogen atom or an organic residue, R.sup.1 is halogen atom, or an organic group, R.sup.2 is hydrogen or halogen atom, C.sub.1 -C.sub.4 alkyl or alkoxy group, R.sup.3 is hydrogen atom, C.sub.1 -C.sub.4 alkyl or alkoxy group, benzyl or a methylene group and R.sub.4 is an organic residue are disclosed. Compounds (Ia) and (Ib) are endowed with elastase inhibitory activity. A two-step process for their preparation starting from the corresponding 4-carboxy cephem or 3-carboxy penam is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.