Amine rich fluorinated polyurethaneureas and their use in a method to immobilize an antithrombogenic agent on a device surface
US5077372A · kind A · utility
37Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 1991 |
| Grant date | Dec 31, 1991 |
| Priority date | — |
| Expiry date | Mar 20, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31551
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.