Patent · US Expired

Fibrionolytic composition

US5078995A · kind A · utility

28Cited by
22References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 11, 1990
Grant dateJan 7, 1992
Priority date
Expiry dateMay 11, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/49
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In accordance with present invention, a method is provided for reducing tissue damaged by ischemia in animal or human. The method comprises injecting an effective amount of an anticoagulant and a surface-active copolymer into an animal or human with tissue damaged by ischemia tissue. The surface-active copolymer can be an ethylene oxide-propylene oxide condensation product with the following general formula: EQU HO(C.sub.2 H.sub.4 O).sub.b (C.sub.3 H.sub.6 O).sub.a (C.sub.2 H.sub.4 O).sub.b H wherein a is an integer such that the hydrophobe represented by (C.sub.3 H.sub.6 O) has a molecular weight of approximately 950 to 4000, preferably approximately 1200 to 3500, and b is an integer such that the hydrophile portion represented by (C.sub.2 H.sub.4 O) constitutes approximately 50% to 90% by weight of the compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.