Modified eglin proteins
US5079229A · kind A · utility
4Cited by
2References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 7, 1989 |
| Grant date | Jan 7, 1992 |
| Priority date | — |
| Expiry date | Mar 7, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/855
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel elgin mutants that differ from the natural eglins B and C by the replacement of one, two or three amino acids in the region of the active center (amino acids 45 and 46, Leu-Asp) by other amino acids are provided. The mutants, which can be produced by recombinant genetic engineering, have valuable pharmacological properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.