2-,21-Dinoreburnamenines containing a 15-aminated group
US5081120A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 23, 1990 |
| Grant date | Jan 14, 1992 |
| Priority date | — |
| Expiry date | Feb 23, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound selected from the group consisting of a compound of the formula (I): ##STR1## in which R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, an alkyl of 1 to 5 carbon atoms, --(CH.sub.2).sub.n --OH in which n is between 2 and 5, an aryl or arylalkyl of 7 to 12 carbon atoms, these two radicals being optionally substituted, ##STR2## in which R.sub.3 is an alkyl of 7 to 12 carbon atoms, these two radicals being optionally substituted, with the proviso that R.sub.1 and R.sub.2 are not both aryl simultaneously, or R.sub.1 and R.sub.2 form, together with the nitrogen atom to which they are linked, a saturated or unsaturated heterocyclic which can contain a second heteroatom chosen from oxygen, sulphur and nitrogen optionally substituted by an alkyl of 1 to 5 carbon atoms, aryl, arylalkyl of 7 to 12 carbon atoms, these radicals being optionally substituted, R.sub.4 and R.sub.5 are individually selected from the group consisting of hydrogen, halogen, alkyl or alkoxy of 1 to 5 carbon atoms, hydroxy, trifluoromethyl or nitro, the said products of formula (I) being in all the possible enantiomeric and diastereoisomeric forms and its non-toxic, pharmac…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.