1,2,3-triazole compounds active as inhibitors of the enzyme HMG-CoA reductase and pharmaceutical compositions containing them
US5081136A · kind A · utility
17Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 13, 1990 |
| Grant date | Jan 14, 1992 |
| Priority date | — |
| Expiry date | Dec 13, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3 and Z have the meanings reported in the specification, and intermediates for their preparation are described. The compounds of formula I have antiatherosclerotic activity as inhibitors of the enzyme HMG-CoA reductase and they are useful in the pharmaceutical field. Compositions for pharmaceutical use containing a compound of formula I as active ingredient are described too.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.