Regiospecific carbonylation process for making acyl compounds from aromatic heterocycles and olefins
US5081250A · kind A · utility
0Cited by
2References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 15, 1989 |
| Grant date | Jan 14, 1992 |
| Priority date | — |
| Expiry date | Aug 15, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/50
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A regiospecific, catalyzed process for preparing acyl derivatives of aromatic nitrogen-containing heterocyclic compounds in which the keto group is selectively added ortho to the nitrogen atom on the aromatic ring. In the presence of a ruthenium carbonyl compound, carbon monoxide and an olefin, the aromatic heterocyclic compound which has an unsubstituted carbon atom ortho to at least one of the heterocyclic atoms adds the acyl group essentially completely in ortho position.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.