Piperidine derivatives and therapeutic and preventive agents for arrhythmia containing same
US5082850A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 22, 1990 |
| Grant date | Jan 21, 1992 |
| Priority date | — |
| Expiry date | Aug 22, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A piperidine compound has the generic formula and is useful to treat arrhythmia. ##STR1## in which R1 is a lower alkyl and W is: ##STR2## X is --S--, --SO-- or --SO2--, R2 is hydrogen or --(CH2)n--Y, n is an integer of 1 to 5, Y is an aryl, pyridyl or a substituted pyridyl, X' is --CO-- or --CH(OH)--, PA1 p is an integer of 1 to 4, R12 is hydrogen or a lower alkyl, Y' is --(CH2)m--A, m is 1 or 2, A is an aryl, a substituted aryl, pyridyl or a substituted pyridyl, R12 and Y may form a 5- or 6-membered ring or a 5- or 6-membered ring having one or more substituents and PA1 R22 is hydrogen, a halogen, a lower alkyl, a lower alkoxy or hydroxy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.